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Based upon these findings on
2019-07-13
Based upon these findings on portions A and B, novel scaffolds of EP4 antagonist, and (R & R=()-Me; =Cl; R=H), shown in , were identified. We next focused on optimizing portion C of these scaffolds.
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Effects of estrogens on bone Estrogens play an important
2019-07-12
Effects of estrogens on bone Estrogens play an important role in bone remodeling, as demonstrated by studies in mice in which the ER genes were deleted [21], [22].
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Enhanced responses to varying concentrations of bronchoconst
2019-07-11
Enhanced responses to varying concentrations of bronchoconstrictors, such as MCh, and airway obstruction are characteristic of Arotinoid Acid and common to other clinical states, including chronic obstructive pulmonary disease, lung transplantation, and infection- or chemical agent-induced airway inflammation (Kuhn et al., 2000).
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Although we observed increases in
2019-07-10
Although we observed increases in α1-AR mediated cAMP production separately in the nucleus and cytoplasm, compartment specificity was observed for PKA activation.
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Interestingly some drugs have been shown to be effective in
2019-07-09
Interestingly, some drugs have been shown to be effective in the regulation of cytokine production (such as IL-2, IL-10, IL-27, IL-35, IL-37 and transforming growth factor-β, TGF-β) and, therefore, having a key role in the management of certain inflammatory-based clinical conditions (Banchereau et al., 2012).
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Recently Schenck et al identified an active site asparagine
2019-07-08
Recently, Schenck et al. [25] identified an active site asparagine 222 (N222) residue in the Glycine max TyrAp/PDH (GmPDH1) that is responsible for its prephenate substrate specificity.
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The instructive precedent for galectin phosphorylation is hu
2019-07-05
The instructive precedent for galectin phosphorylation is human galectin-3 (hGal-3).
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Recently several Pt IV complexes
2019-07-04
Recently, several Pt(IV) complexes as prodrugs have been designed and studied to enhance anti-tumor efficacy of traditional Pt(II) drugs, improving their cellular uptake and blood-circulation time [26], [27], [28], [29].
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Accurate equilibrium predictions of CO containing mixtures
2019-07-03
Accurate equilibrium predictions of CO2 containing mixtures, however, are challenging with traditional equations of state.
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SCR7 br Conclusion Introduction Biological wastewater treatm
2019-07-02
Conclusion Introduction Biological wastewater treatment is targeted towards the removal of phosphorous, nitrogen and organic substances by the metabolic activity of a diverse activated sludge microbial community.
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Pero en los a os noventa
2019-07-01
Pero en los años noventa, como refere Brito, al inventariarse los resultados de la estrategia de desarrollo y de las reformas adelantadas en la década anterior, es decir ante una revisión “crítica” del “Consenso de Washington”, fue evidente que los costos en términos de inequidad y dualización social fueron mayores que sus beneficios, en tanto crecimiento, estabilidad económica y eficiencia pública.
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With the availability of vaccines screen and treat approache
2019-06-29
With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement.
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br Materials and methods br Results br Discussion
2019-06-28
Materials and methods
Results
Discussion The treatment regimen used in this study is generally safe and well tolerated. -
Interpretation Stakeholders from sectors not historically en
2019-06-27
Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care.
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Methods The FMSTP accepts Basotho doctors after they have co
2019-06-27
Methods The FMSTP accepts Basotho doctors after they Beta-Sheet Breaker Peptide iAβ5 have completed medical school and at least 1 year of internship.
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