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This work is inspired by the systematic work of Coutinho
2020-11-05
This work is inspired by the systematic work of Coutinho and co-workers, who obtained several very useful experimental data, which will be also used in our work, and applied the CPA equation of state for the modeling of systems relevant to the production of biodiesel [8], [9], [10], [11], [12], [13]
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It is known that cigarette smoke increases the oxidative bur
2020-11-04
It is known that cigarette smoke increases the oxidative burden in the lungs of mice with emphysema, which leads to oxidative stress [[34], [35], [36]]. However, in addition to cigarette smoke, studies have shown that endogenous oxidative stress is associated with proteolytic scopolamine hydrobromid
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As an endogenous negative modulator CRBN inhibits AMPK s
2020-11-04
As an endogenous negative modulator, CRBN inhibits AMPK’s activation (phosphorylation of Thr172) by directly binding to the α-subunit of AMPK, disrupting γ-subunit recruitment to the AMPK complex (Lee et al., 2011, Lee et al., 2013). In our study, we did not focus on AMPK activation, since only a si
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br Development of the double strand break
2020-11-04
Development of the double strand break repair model for meiotic recombination Meiotic recombination was first described by Frans Alfons Janssens using Clobetasol propionate in the salamander Batracoseps attenuatus in 1909 [21] and then further elaborated at the genetic level in Drosophila by Tho
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It is well known that CysLTs exert potent contractile
2020-11-04
It is well known that CysLTs exert potent contractile action on human bronchial smooth muscles through activation of CysLT1 receptors. Indeed, in vitro antigen-induced contraction of passively sensitized human bronchial tissue is markedly suppressed by a pre-treatment with CysLT1 receptor antagonist
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Taking into account that a PFOS inhibits CRF gene expression
2020-11-04
Taking into account that: (a) PFOS inhibits CRF gene expression as well as CRF and corticosterone secretion (Pereiro et al., 2014); (b) CRF1r mediates the stimulation of the pituitary ACTH secretion by this neuropeptide (Rivier et al., 2003); (c) corticosterone regulates its own synthesis by a negat
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Population genetic summary statistics for five super and sub
2020-11-04
Population genetic summary statistics for five super- and 26 sub-populations, including haplotype and diplotype frequencies (analogous to allele and genotype frequencies), observed (Ho) and expected (He) heterozygosities, pairwise genetic distances, and tests for detection of departures from Hardy W
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Notochord is a transient structure differentiating
2020-11-04
Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated na+/ca2+ exchanger surrounded by a unique ECM structure improperly called notochordal BM. As in chicken and
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As mentioned above of various
2020-11-04
As mentioned above, of various constitutive models, the Chaboche kinematic model was widely used [3,7,[23], [24], [25], [26], [27]]. There exist many significant literature around the Chaboche/Chaboche type plasticity model calibration and its parameter determination methods. Aguis et al. [28] emplo
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br Introduction Oral contraceptives OCs are the
2020-11-04
Introduction Oral contraceptives (OCs) are the most commonly used medication for contraception all over the world and are also used in the treatment of menstrual disturbances and hyperandrogenism in women with polycystic ovary syndrome [1]. The impact of OC steroids on cardiovascular pathophysiol
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Together the data suggests that more work needs to
2020-11-04
Together, the data suggests that more work needs to be done to establish the role of PARP inhibitors in Ewing sarcoma. As a single agent, there is some activity in Ewing sarcoma cell lines and a highly statistically significant relationship between olaparib sensitivity and EWS–FLI1 expression. Howev
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Toremifene Our present results support a
2020-11-04
Our present results support a major role of EP1 receptors in peripheral heat sensitization and a smaller contribution to central heat sensitization but no contribution to mechanical sensitization. While the contribution of peripheral EP1 receptors to heat hyperalgesia is in good agreement with the
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1,3-PBIT dihydrobromide More recent studies have correlated
2020-11-04
More recent studies have correlated sPLA2-V with alternative macrophage activation (M2) in human and murine macrophages [149,150]. sPLA2-V expression was induced during both human and mouse interleukin-4–mediated activation of macrophages in vitro, and its absence impaired macrophage activation in v
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Given the widespread occurrence of
2020-11-03
Given the widespread occurrence of oncogene-induced RS and the increasing clinical interest in small molecule inhibitors that further exacerbate RS in human cancers (such as ATR inhibitors), our findings point to a protective role for RAD52 in the maintenance of cancer cell viability. As such, RAD52
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In the belief that DNA based
2020-11-03
In the belief that DNA-based nanosensors and DNA microarrays should be easier to operate, faster, more accurate and more economically viable than PCR-based techniques, an electrochemical DNA biosensor was designed for detection of G. boninense[9], [10]. This was developed based on a gold electrode m
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