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Thus a majority of known chemical and physico chemical metho
2024-12-26
Thus, a majority of known chemical and physico-chemical methods of metallic ions assay has a number of disadvantages, such as a low sensitivity and selectivity, high costs and complexity of the equipment. Therefore, the development of simple cost-effective sensitive methods of quantitative analysis
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br Drugs with documented pro apoptotic effects on platelets
2024-12-26
Drugs with documented pro-apoptotic effects on platelets More than 200 drugs are reported to cause thrombocytopenia [5,42]. The concept of platelet apoptosis is relatively new and was only recently evaluated in the context of drug-induced thrombocytopenia [43]. Table 2 lists the drugs presently k
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The objectives of this study
2024-12-26
The objectives of this study were to investigate 1) the mRNA and protein expression of apelin and APJ in porcine ovarian follicles of different sizes, and their immunolocalization and concentrations in follicular fluid and ovarian follicle, and 2) the direct effect of recombinant human apelin-13 on
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Bamboo the fastest growing multipurpose woody plant
2024-12-26
Bamboo, the fastest growing, multipurpose woody plant with a myriad of industrial and domestic uses is intricately associated with the cultural, social and economic conditions of people in many Asian countries. Its uses are not only limited to being used as a substitute for wood in construction, fur
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Previous studies demonstrate that chiral biointerface has gr
2024-12-26
Previous studies demonstrate that chiral biointerface has great influence on cells adhesion and proteins adsorption [39], [40], [41], [42], [43], which inspired us to further develop antimicrobial materials or surfaces by taking advantage of the “chiral taste” of microbes. L-borneol is a hydrophobic
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Rilmenidine α2-adrenoceptor agonist br Materials and methods
2024-12-25
Materials and methods Results Discussion Wound healing of the human cornea is a complex process that requires cell migration and proliferation. Corneal wound healing is characterized by major changes in the composition of the ECM such as a massive transitory secretion of fibronectin combine
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br Adenosine as a mediator of procedures used to
2024-12-25
Adenosine as a mediator of procedures used to manage pain The issue of caffeine Caffeine, from dietary sources, is perhaps the most widely consumed behaviorally active agent in the world (Fredholm et al., 1999). Initial characterization indicated caffeine had a higher affinity at A1−, A2A− and
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br Introduction br Rac dependent ROS and actin
2024-12-25
Introduction Rac1-dependent ROS and Isobutylmethylxanthine regulation in neuronal functions NOX-mediated ROS have an important role as physiological messengers. One remarkable example regarding such a function is during axonal formation. In this line, increased p40phox/NOX2 levels and co-loca
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Encouraged by this observation a
2024-12-25
Encouraged by this observation, a systematic SAR study on the A ring -alkoxy was conducted as summarized in . The A ring methoxy-containing KRCA-0008 was proven an optimal substituent in terms of potency after all and its bigger size derivatives were detrimental in both biochemical and H3122 cellula
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ACE inhibition is often thought to play a
2024-12-25
ACE inhibition is often thought to play a central role in the mechanisms of blood pressure reduction in vivo, and most ACE inhibitory (ACEi) peptides were characterized based on in vitro ACE inhibition. A relationship between in vitro ACE inhibition and antihypertensive activity, however, is not app
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br Introduction S http www apexbt
2024-12-25
Introduction Systemic lupus erythematosus (SLE) is a group of systemic autoimmune disorders characterized by anti-nuclear Vomiting control (ANA), rashes and photosensitivity, joint inflammation, nephritis, and other clinical criteria. SLE develops through the breakdown of three major checkpoints
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Endoplasmic reticulum ER stress resulting from accumulation
2024-12-25
Endoplasmic reticulum (ER) stress resulting from accumulation of misfolded proteins in ER lumen stimulates a chain of adaptive responses termed as the unfolded protein response (UPR). Glucose related protein (GRP78/BiP), key ER chaperone essential for the activation of the ER-transmembrane signaling
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br The Molecular Machinery of Autophagy
2024-12-25
The Molecular Machinery of Autophagy and Regulation by Sphingolipids Sphingolipid-Mediated Autophagy in Cancer: Dr. Jekyll and Mr. Hyde Autophagy is an evolutionarily conserved stress response that typically promotes survival and antagonizes apoptosis. However, excessive autophagy was found to
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br Regulation of V ATPase
2024-12-25
Regulation of V-ATPase assembly in response to changes in amino AZD6738 levels A central regulator of cell growth and metabolism is mTORC1 [38]. mTORC1 integrates signals from nutrient availability and growth factor receptors to control such processes as protein and lipid synthesis and autophagy
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For the TSH receptor signaling at the Golgi trans Golgi
2024-12-24
For the TSH receptor, signaling at the Golgi/trans-Golgi network appears required for both rapid effects of TSH − such as SR 95531 hydrobromide mg depolymerization, which is implicated in thyroglobulin reuptake and, thus, thyroid hormone release − and late ones, such as those on gene transcription.